Fig. 2.
Oxr1 interacts with the glycolytic enzyme, glucose-6-phosphate isomerase. a Co-immunoprecipitation in HeLa cells over-expressing MYC-tagged Gpi1 with HA-tagged Oxr1-FL or Oxr1-C. b Gpi1 activity from whole cerebellum or remaining brain tissue of Oxr1d/d mice compared to Oxr1+/+ controls (N = 4–8 animals per group). c Gpi1 activity in N2a cells transfected with an shRNA against either Oxr1 or Gpi1 or corresponding control vector (shRNA scramble) (N = 4 independent repeats). Panel b: t test, panel c: one-way ANOVA; **p < 0.01