Table 2. Incidence of neonatal outcomes and unadjusted linear (quantitative outcomes) or logistic (dichotomous outcomes) regression analysis.
|
No IUI Group 0 n = 673 |
HCA Group 1 n = 73 |
HCA+Fun 1 Group 2 n = 34 |
HCA+Fun 2–3 Group 3 n = 27 |
RC/ORs and CI (1 vs 0) |
RC/ORs and CI (2 vs 0) |
RC/ORs and CI (3 vs 0) |
|
|---|---|---|---|---|---|---|---|
|
Apgar at 1 min (median, range) |
8, 0–10 | 8, 0–9 | 5,5, 1–9 | 5, 1–9 | -0.3 -0.8; 0.1 |
-1.5 -2.1; -0.8 |
-2.5 -3.2; -1.7 |
|
Apgar at 5 min (median, range) |
9, 2–10 | 9, 3–10 | 8, 5–10 | 8, 3–10 | -0.2 -0.6; 0.1 |
-0.8 -1.2; -0.3 |
-1.4 -1.8; -0.9 |
| Resuscitation at birth (%) | 320/673 (47.5) |
40/73 (54.8) |
31/34 (91.2) |
24/27 (88.9) |
1.3 0.8; 2.2 |
11.4 3.4; 38.3 |
8.8 2.6; 29.6 |
| Oxygen in delivery room (%) | 175/672 (26) |
25/73 (34.2) |
24/34 (70.5) |
19/27 (70.4) |
1.5 0.8; 2.6 |
6.8 3.1; 14.5 |
6.7 2.9; 15.7 |
| Mechanical ventilation (%) | 128/673 (19) |
13/73 (17.8) |
19/34 (55.8) |
14/27 (51.8) |
0.9 0.4; 1.8 |
5.4 2.6; 11.1 |
4.6 2.1; 10.1 |
| Mechanical ventilation (days) | 2.1 | 3.9 | 8.5 | 15.6 | 1 -1.8; 3.8 |
5.4 1.4; 9.5 |
12.2 7.6; 16.7 |
| Non-invasive ventilation (%) | 364/673 (54.1) |
39/73 (53.4) |
26/34 (76.5) |
20/27 (74.1) |
0.9 0.6; 1.6 |
2.8 1.2; 6.1 |
2.4 1; 5.8 |
| Non-invasive ventilation (days) | 10.8 | 16.3 | 30 | 26.7 | 2.6 -3.9; 9 |
11.9 2.6; 21.3 |
13.6 2.9; 24.2 |
| Surfactant use (overall) | 204/673 (30.3) |
21/73 (28.8) |
19/34 (55.9) |
17/27 (62.9) |
0.9 0.5; 1.7 |
2.9 1.5; 5.7 |
3.9 1.7; 8.7 |
| Surfactant use (>1 dose) | 67/673 (9.9) |
9/73 (12.3) |
10/34 (29.4) |
11/27 (40.7) |
1.2 0.5; 2.9 |
4.6 2; 10.7 |
7.7 3.1; 18.9 |
|
RDS (%) |
341/673 (50.7) |
41/73 (56.2) |
30/34 (88.2) |
23/27 (85.2) |
1.2 0.7; 2.1 |
7.3 2.5; 21.3 |
5.6 1.9; 16.4 |
|
EOS (%) |
3/673 (0.45) |
1/73 (1.37) |
4/34 (11.8) |
2/27 (7.41) |
3.1 0.3; 30.3 |
29.8 6.3; 100 |
17.8 2.8; 100 |
|
LOS (%)* |
43/672 (6.4) |
8/72 (11.1) |
6/33 (18.2) |
8/27 (29.6) |
1.8 0.8; 4.4 |
3.3 1.3; 8.2 |
6.2 2.5; 15 |
|
PDA (%) |
72/673 (10.7) |
10/73 (13.7) |
11/34 (32.4) |
12/27 (44.4) |
1.3 0.6; 2.7 |
4 1.9; 8.4 |
6.7 2.9; 15 |
|
IVH (%) |
40/673 (5.9) |
7/73 (9.59) |
9/34 (26.5) |
9/27 (33.3) |
1.7 0.6; 4.2 |
5.7 2.3; 13.7 |
7.9 3.3; 18.9 |
|
ROP (%)* |
21/661 (3.2) |
7/70 (10) |
6/30 (20) |
7/25 (28) |
3.4 1.2; 9.1 |
7.6 2.5; 23.2 |
11.8 4.4; 31.8 |
|
BPD (%)* |
60/656 (9.2) |
13/70 (18.6) |
9/28 (32.1) |
10/23 (43.5) |
2.3 1.1; 4.7 |
4.7 1.9; 11.8 |
7.6 3.2; 18.4 |
| Death before discharge (%) | 19/673 (2.8) |
5/73 (6.9) |
6/34 (17.6) |
5/27 (18.5) |
2.5 0.9; 6.9 |
7.4 2.7; 19.9 |
7.8 2.6; 23.1 |
*percentage is calculated on survived neonates