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. 2019 Jan 29;13(1):e0007111. doi: 10.1371/journal.pntd.0007111

Table 2. Comparison of disability adjusted life years and clinical trials for each neglected tropical disease among children.

Condition* Pediatric Global Burden of Disease
(per 1,000 DALYs)
Pediatric Trials, n DALYs per Trial (1,000 DALYs)a DALYs per Participantb
Dengue and Chikungunya 1,208 22 53 15
Schistosomiasis 371 14 25 52
Soil Transmitted Helminthiases 1,578 9 158 187
Leishmaniasis 721 5 120 1,689
Rabies 601 3 150 1,114
Chagas 3 2 1 8
Scabies and other Ectoparasites 1,507 2 502 2,833
Trachoma 0 2 0 0.1
Human African Trypanosomiasis 118 1 59 947
Taeniasis/Cysticercosis 31 1 16 316
Dracunculiasis 0 0 0 -
Echinococcosis 60 0 60 -
Foodborne Trematodiases 139 0 139 -
Leprosy 0 0 0 -
Lymphatic Filariasis 242 0 242 -
Onchocerciasis 273 0 273 -
Total 6,855 61 89 196

*Buruli ulcer, mycetoma, snakebite envenoming, and yaws are not included as the Global Health Data Exchange does not include DALYs for these diseases.

aCalculated by dividing the pediatric global burden of disease (per 1,000 DALYs) by the number of pediatric trials for each NTD. To allow for representation of conditions that do not have any clinical trials, we added 1 trial to each condition.

bCalculated by dividing the pediatric global burden of disease (per 1,000 DALYs) by the number of trial participants for each NTD.