Table 2. Comparison of disability adjusted life years and clinical trials for each neglected tropical disease among children.
Condition* | Pediatric Global Burden of Disease (per 1,000 DALYs) |
Pediatric Trials, n | DALYs per Trial (1,000 DALYs)a | DALYs per Participantb |
---|---|---|---|---|
Dengue and Chikungunya | 1,208 | 22 | 53 | 15 |
Schistosomiasis | 371 | 14 | 25 | 52 |
Soil Transmitted Helminthiases | 1,578 | 9 | 158 | 187 |
Leishmaniasis | 721 | 5 | 120 | 1,689 |
Rabies | 601 | 3 | 150 | 1,114 |
Chagas | 3 | 2 | 1 | 8 |
Scabies and other Ectoparasites | 1,507 | 2 | 502 | 2,833 |
Trachoma | 0 | 2 | 0 | 0.1 |
Human African Trypanosomiasis | 118 | 1 | 59 | 947 |
Taeniasis/Cysticercosis | 31 | 1 | 16 | 316 |
Dracunculiasis | 0 | 0 | 0 | - |
Echinococcosis | 60 | 0 | 60 | - |
Foodborne Trematodiases | 139 | 0 | 139 | - |
Leprosy | 0 | 0 | 0 | - |
Lymphatic Filariasis | 242 | 0 | 242 | - |
Onchocerciasis | 273 | 0 | 273 | - |
Total | 6,855 | 61 | 89 | 196 |
*Buruli ulcer, mycetoma, snakebite envenoming, and yaws are not included as the Global Health Data Exchange does not include DALYs for these diseases.
aCalculated by dividing the pediatric global burden of disease (per 1,000 DALYs) by the number of pediatric trials for each NTD. To allow for representation of conditions that do not have any clinical trials, we added 1 trial to each condition.
bCalculated by dividing the pediatric global burden of disease (per 1,000 DALYs) by the number of trial participants for each NTD.