. Author manuscript; available in PMC: 2020 Mar 1.

Published in final edited form as: Diabetes Obes Metab. 2018 Dec 3;21(3):683–690. doi: 10.1111/dom.13572

Table 2:

BMI and hormonal changes after VSG or RYGB (Study 3 – Second bariatric study)

		Months after bariatric surgery
	OP	0 (a)	3 (b)	6 (c)	12 (d)	P
BMI	All	49.7 ± 6.9^b,c,d	41.2 ± 6.2^a,c,d	36.5 ± 5.7^a,b,d	32.9 ± 6.2^a,b,c	<0.001
(kg/m²)	VSG	50.9 ± 7.5^b,c,d	42.9 ± 6.6^a,c,d	37.4 ± 6.2^a,b,d	34.4 ± 6.7^a,b,c	<0.001
	RYGB	48.0 ± 6.0^b,c,d	39.1 ± 5.3^a,c,d	35.3 ± 4.9^a,b,d	30.8 ± 5.2^a,b,c	<0.001

Glucose	All	100.5 (94.0, 112.5)^b,c,d	91.5 (87.0, 98.0)^a	90.5 (85.0, 98.8)^a	88.5 (84.8, 97.3)^a	<0.001
(mg/dl)	VSG	108.0 (94.0, 123.0)^c,d	90.0 (86.5, 98.0)	90.0 (85.0, 97.0)^a	89.0 (83.0, 98.0)^a	<0.001
	RYGB	99.0.(94.0, 103.0)^b,c,d	92.5 (88.3, 100.0)^a	91.0 (85.0, 101.0)^a	88.0 (85.0, 94.0)^a	0.40

Insulin	All	23.1 (15.9, 28.1)^b,c,d	9.5 (7.9, 12.7)^a	8.7 (7.2, 12.9)^a	8.7 (7.2, 12.9)^a	<0.001
(ulU/ml)	VSG	24.3 (19.0, 29.0)^b,c,d	8.2 (7.2, 14.1)^a	10.9 (7.2, 13.0)^a	10.9 (7.2, 13.0)^a	0.003
	RYGB	22.3 (15.1, 26.0)^b,c,d	9.7 (8.4, 10.9)^a	8.3 (7.1,10.2)^a	8.3 (7.1, 10.2)^a	<0.001

HOMA-IR	All	5.76 ± 2.28 ^b,c,d	2.35 ± 1.29^a	2.25 ± 1.13^a	2.22 ± 1.14^a	<0.001
	VSG	6.26 ± 2.52^b,c,d	2.36 ± 1.45^a	2.35 ± 1.09^a	2.33 ± 1.15^a	<0.001
	RYGB	5.05 ± 1.78^b,c,d	2.33 ± 1.11^a	2.11 ± 1.22^a	2.06 ± 1.18^a	<0.001

HOMA-β	All	201.4 ± 61.2^b,c,d	116.5 ± 50.8^a	124.6 ± 56.6^a	132.3 ± 67.9^a	<0.001
(%)	VSG	193.9 ± 67.8^b,d	99.7 ± 45.1^a	136.3 ± 63.2	137.5 ± 62.9^a	0.006
	RYGB	214.7 ± 47.9^b,c,d	135.0 ± 52.3^a	109.7 ± 45.5^a	125.4 ± 77.4^a	<0.001

Follistatin	All	4.29 (3.28. 5.33)^b,c,d	3.76 (3.41, 4.25)^a,d	3.25 (2.80, 4.04)^a	3.22 (2.25, 3.44)^a,b	<0.001
(ng/ml)	VSG	3.95 (3.25, 4.89)^d	3.73 (3.19, 4.24)^d	3.20 (2.82, 4.12)	3.07 (2.25, 3.26)^a,b	0.003
	RYGB	4.82 (3.57, 5.48)^d	3.85 (3.56, 4.33)	3.30 (2.74, 4.01)	3.44 (2.16, 4.33)^a	0.02

FSTL3	All	15.9 (13.9, 17.1)^c	14.3 (12.6, 17.4)^c	12.7 (10.8,15.2)^a,b	13.0 (10.8, 16.0)	<0.001
(ng/ml)	VSG	16.1 (14.7, 17.1)^c,d	14.2 (12.5, 17.3)^c,d	12.7 (11.2, 15.9)^a,b	12.1 (10.5, 14.6)^a,b	<0.001
	RYGB	14.2 (12.1, 19.1)	14.4 (12.8, 18.0)	12.1 (10.4, 15.1)	13.9 (11.7, 20.2)	0.25

^†

Data are presented as mean ± SD if normally distributed and as median with first and third quartile if not normally distributed.

^‡

An intention-to treat analysis was performed. P-overall corresponds to the p-value of paired one-way ANOVA.

^§

By p-overall<0.05, post-hoc Tukey’s test between groups were performed. Superscript letters (a,b,c,d) indicate p<0.05 in post-hoc t-test between the subject group of the column in which the letters are written vs. the group indicated by the letter (a, b, c or d)