Fig. 5.

Effects of quercetin and isorahmnetin on hepatic uric acid levels and xanthine oxidase (XO) activity in hyperuricemic mice. a and b Indicate liver uric acid levels in the mice treated with quercetin and isorhamentin, respectively. c and d Show liver XO activity in the mice treated with quercetin and isorhamentin, respectively. Each value represents mean ± SEM for 8–12 mice (duplicate measurement per mouse). For statistical significance, *P < 0.05 and **P < 0.01 when the treated groups were compared with the model control group (Dunnett’s test)