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. 2019 Feb 8;4:8. doi: 10.1038/s41541-019-0104-x

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Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 4 — Viral burden and serological analysis of long-term vaccination with VSVΔG-LASVGPC. TCID₅₀ analysis of serum, liver, lung and spleen collected from animals vaccinated a 189 DPV and b 355 DPV (T-test; Holm-Sidak). Total LASVGPC-specific IgG titers were assessed by endpoint titration and the Log ECF₉₀ for each time-point calculated for animals challenged c 189 DPV and d 355 DPV, respectively. Data are presented as mean values with error bars indicating SEM. p = 0.1234 (ns), 0.0332 (*), 0.0021 (**), 0.0002 (***), <0.0001 (****)