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. 2019 Feb 9;17:19. doi: 10.1186/s12958-019-0462-2

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© The Author(s). 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 6 — Ultrastructure of the Leydig cell. Abundant vesicular endoplasmic reticulum (a), and tubular endoplasmic reticulum and mitochondria (b) appear close to the nucleus and also show the nucleus pores (white arrow). Lipid droplets exhibit closely with vesicular endoplasmic reticulum during reproductive phase (c). In hibernation, the tubular endoplasmic reticulum, mitochondria and lysosome appeared to be in contact with the lipid droplets (d). The endoplasmic reticulum in contact with a lipid droplet (white dotted square) and with a lipid droplet and the mitochondria (black dotted square). Tight junctions between Leydig cell are also seen (black thick arrow). Mitochondria with well-developed inter cristae tubules (e-f). N: nucleus; ER: endoplasmic reticulum; LD: lipid droplets; M: mitochondria; L: Lysosome. Scale bar = 600 μm (a-b), 2 μm = (c-d) and 600 μm (e-f)