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. 2019 Feb 9;17:19. doi: 10.1186/s12958-019-0462-2

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© The Author(s). 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 8 — Electron micrograph of lipid droplet mobilization during hibernation. (a) The Leydig cell contains numerous small lipid droplets that appear closely to the lysosome and mitochondria. (b) Large lipid droplets in contact with each other (black thick arrow) and with the lysosome (black head arrow) and mitochondria (white thick arrow). A curved arrow indicates the autophagic tube, (black arrow) intermediate filaments, (black rectangular area) autolysosome, autophagosome and isolated membrane. The white rectangular area indicates the (a) fusion of autophagosome and lysosome, and the (b) lysosomal engulfing of the LD. The illustration is of a higher magnification. LD: Lipid droplets; M: Mitochondria; L: Lysosome; A: Autophagosome; AL: Autolysosome; IM: Isolated Membrane. Scale bar = 1 μm (a-d)