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. 2019 Feb 9;20:68. doi: 10.1186/s12891-019-2453-z

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© The Author(s). 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 1 — Scheme of this study protocol. CT, computed tomography; ECG, electrocardiogram; MRI, magnetic resonance imaging; PET, positron emission tomography; XP, X-ray photograph; CTCAE, common terminology criteria for adverse events; CR, complete response; PR, partial response; SD, stable disease; PD, progressive disease; FDG, ¹⁸F-fluorodeoxyglucose; MSTS, Musculoskeletal Tumor Society