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. 2019 Feb 8;18:43. doi: 10.1186/s12944-018-0938-7

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© The Author(s). 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 4 — Histological sections of hippocampus. a Cell dispersion (black arrow) and thickness (white arrow) of the hippocampal CA1 zone, at 12 months of aging. Nissl 40x. b Histopathological analysis. Data are expressed as mean ± SEM * Indicate significant difference to Control eSS at the end of 12 months, p ≤ 0.05