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. 2019 Feb 8;12:11. doi: 10.1186/s13041-019-0428-5

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© The Author(s). 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 4 — Typical synaptosomes. Note: Typical synaptosomes examined by electron microscopy (EM). Synaptosomes were prepared with a Percoll gradient procedure. EM showed the presence of intact synaptic vesicles and the preservation of presynaptic and postsynaptic elements and a higher mitochondrial content and contained a few extrasynaptic mitochondria. Scale bar is 0.5 μm in (a and b) and 1 μm in (c and d)