Table 4.
Group | Week 0 | Week 1 | Week 2 | Week 3 | Week 4 |
---|---|---|---|---|---|
WKY + saline | 7.09 ± 0.68 | 6.71 ± 1.25 | 6.00 ± 1.16 | 4.66 ± 1.03 | 4.01 ± 1.28 |
SHR + saline | 20.46 ± 1.45## | 17.37 ± 0.91## | 18.51 ± 1.03## | 17.65 ± 1.34## | 18.23 ± 1.54## |
SHR + MPH(1.5 mg/kg) | 18.73 ± 1.07 | 11.56 ± 1.10** | 8.81 ± 1.29** | 6.80 ± 1.45** | 4.10 ± 1.42** |
SHR + baicalin(50 mg/kg) | 18.36 ± 1.00 | 16.75 ± 1.67 | 15.93 ± 1.50 | 11.08 ± 0.47* | 9.98 ± 1.29** |
SHR + baicalin(100 mg/kg) | 19.75 ± 1.61 | 16.54 ± 1.06 | 10.16 ± 0.89** | 8.76 ± 1.17** | 5.95 ± 0.72** |
SHR + baicalin(150 mg/kg) | 18.15 ± 1.14 | 13.41 ± 0.98* | 9.12 ± 1.02** | 6.84 ± 1.92** | 4.64 ± 1.14** |
Note: Comparison of the moving speed in open field test in all groups; values are expressed as the mean ± S.E.M. #p < 0.05 and ##p < 0.01 versus WKY + saline group; *p < 0.05 and **p < 0.01 versus SHR + saline group