Table 4.
<160 mm Hg | 160-179 mm Hg | ≥180 mm Hg | P value for homogeneity | ||||
---|---|---|---|---|---|---|---|
Odds Ratio (95% CI) | P value | Odds Ratio (95% CI) | P value | Odds Ratio (95% CI) | P value | ||
14 days or hospital discharge | |||||||
Composite death or major disability | 1.12 (0.82 to 1.52) | 0.47 | 1.10 (0.84 to 1.44) | 0.48 | 1.01 (0.69 to 1.46) | 0.97 | 0.63 |
Ordinal modified Rankin score | 1.09 (0.88 to 1.34) | 0.42 | 1.03 (0.86 to 1.25) | 0.73 | 0.90 (0.70 to 1.16) | 0.40 | 0.36 |
All-cause mortality | 2.41 (0.56 to 10.30) | 0.24 | 1.57 (0.57 to 4.36) | 0.39 | 0.08 (0.01 to 0.71) | 0.02 | 0.01 |
3-month post-treatment follow-up visit | |||||||
Composite death or major disability | 1.03 (0.75 to 1.42) | 0.87 | 1.30 (0.98 to 1.73) | 0.07 | 0.84 (0.58 to 1.21) | 0.34 | 0.38 |
Ordinal modified Rankin score | 1.04 (0.84 to 1.28) | 0.74 | 1.07 (0.89 to 1.30) | 0.45 | 0.99 (0.77 to 1.28) | 0.96 | 0.86 |
All-cause mortality | 1.23 (0.55 to 2.71) | 0.62 | 2.27 (1.14 to 4.52) | 0.02 | 0.45 (0.18 to 1.15) | 0.10 | 0.57 |
Recurrent stroke | 0.69 (0.25 to 1.94) | 0.48 | 0.92 (0.43 to 2.00) | 0.84 | 0.49 (0.20 to 1.17) | 0.11 | 0.49 |
Vascular events | 0.72 (0.32 to 1.61) | 0.43 | 1.31 (0.70 to 2.43) | 0.40 | 0.51 (0.23 to 1.14) | 0.10 | 0.46 |
Death or vascular events | 1.06 (0.56 to 2.01) | 0.85 | 1.47 (0.88 to 2.45) | 0.14 | 0.64 (0.34 to 1.20) | 0.16 | 0.20 |
Abbreviations: CI = confidence interval; NIHSS = NIH stroke scale
Adjusting for age, sex, baseline systolic blood pressure, body-mass index, diabetes, cigarette smoking, stroke subtype, and NIH Stroke Scale score at baseline as well as time from onset to randomization.