Table 5.
Strain | lexA | clpP | recNp | recN | Average Cell Area | %Cells (Area>200) | Bumps | Mini cells |
---|---|---|---|---|---|---|---|---|
SS10044 | + | + | + | + | 100 | 0 | 0 | 0 |
SS10047 | 51 | + | + | + | 140 | 8 | 0 | 0.02 |
SS10352 | + | Δ | + | + | 100 | 0 | 0 | 0 |
SS12698 | + | + | + | Δ | 100 | 0 | 0 | 0 |
SS10064 | 51 | Δ | + | + | 270 | 50 | 0.01 | 0.43 |
SS10354 | + | + | op | + | 100 | 0 | 0 | 0 |
SS10355 | + | Δ | op | + | 160 | 15 | 0.02 | 0.05 |
The strains used in this table are all derivatives of BW25113. They have a ΔsulA mutation instead of a sulB103 to prevent SOS filamentation. 2300–3700 cells were counted for each strain. Average Cell Area is given in number of pixels. Bumps and mini-cells are given as a frequency per total number of cells. Cells were grown in as mentioned the Experimental Procedures. All statistical tests were done using the Student’s t-test. The difference in average cell area of ΔclpP lexA51 (SS10064) and either of the single mutants (SS10047 and SS10352) is significant (p < 0.001). Likewise, the difference in average cell area of recNop ΔclpP (SS10355) and either of the single mutants (SS10354 and SS10352) is significant (p < 0.001).