Table 2:
Significant variants from genome-wide association studies of opioid use disorder
| Gene Symbol | Gene Name | Variant | Ethnicity | Opioid-Exposed Controls | References |
|---|---|---|---|---|---|
| Intergenic | - | rs10494334 | European-American | No | [38] |
| APBB2 | Amyloid Beta Precursor Protein Binding Family B Member 2 | rs114070671 | Mixed (African-American, European-American) | No | [39] |
| KCNG2 | Potassium Voltage-Gated Channel Modifier Subfamily G Member 2 | rs62103177 | Mixed (African-American, European-American) | No | [39] |
| KCNC1 | Potassium Voltage-Gated Channel Subfamily C Member 1 | rs60349741 | Mixed (African-American, European-American) | No | [39] |
| CNIH3 | Cornichon Family AMPA Receptor Auxiliary Protein 3 | rs1436175 | European-Australian | Yes | [41] |
| RGMA | Repulsive Guidance Molecule Family Member A | rs12442183 | European-American | Yes | [40] |