Table 3.
Cigarette smoking in relation to risk of incident SLE among women in the Black Women’s Health Study
| Smoking | # Cases | Person years | Age- adjusted HR1 | MV-adjusted HR2 | 95% CI |
|---|---|---|---|---|---|
|
Never smoked |
81 |
610,444 |
1.00(ref) |
1.00(ref) |
--------- |
| Ever smoked | 46 | 317,638 | 1.23 | 1.45 | (0.97–2.18) |
| Current | 20 | 116,338 | 1.25 | 1.52 | (0.90–2.57) |
| Past | 26 | 201,250 | 1.22 | 1.41 | (0.87–2.28) |
| < 20 pack-years | 36 | 248,725 | 1.19 | 1.37 | (0.89–2.11) |
| ≥ 20 pack-years | 10 | 68,913 | 1.43 | 1.60 | (0.79–3.25) |
MV=multivariable, HR=hazard ratio; CI= confidence interval, pack-years=pack-years of smoking
1
Age-adjusted HR was also adjusted for questionnaire cycle.
2
MV adjusted in addition for alcohol consumption, BMI, ever use of oral contraceptives, menopausal status, ever use of menopausal female hormones, quintile of energy intake, years of education and quintile of neighborhood socioeconomic status score.