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. Author manuscript; available in PMC: 2020 Jan 8.
Published in final edited form as: Biochem Biophys Res Commun. 2018 Dec 1;508(2):536–542. doi: 10.1016/j.bbrc.2018.11.155

Figure 2: Mammary gland development in LBH-deficient MMTV-Wnt1 transgenic mice.

Figure 2:

(A) Representative whole-mount images of carmine-red stained mammary glands (MG) from female mice of the indicated genotypes & ages in weeks (wk) (n=3/genotype/age). Note, the outgrowth defects caused by LBH deficiency in non-transgenic K14Cre;Lbh KO (black arrows) and trigenic MMTV-Wnt1;K14Cre-Lbh KO MGs (red arrow). (B) Quantification of pubertal MG outgrowth at 6 and 8 wk (distance between lymph node and the distal tips of the growing ducts). Data represent mean ± s.e.m. (n=3 mice per genotype/developmental stage/two inguinal MGs per animal); P-values (Student’s t-test) are indicated; NS = not significant.