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. 2019 Feb 7;7:e6309. doi: 10.7717/peerj.6309

Figure 5. Correlation of HIF-1α, MDR1 and LAPTM4B expression with clinical features of colon cancer.

Figure 5

Correlation of HIF-1α expression with (A) tumor stage, (B) metastasis, and (C) chemotherapy treatment in colon cancer patients. Correlation of MDR1 expression with (D) tumor stage, (E) metastasis, and (F) chemotherapy treatment in colon cancer patients. Correlation of LAPTM4B overexpression with the (G) tumor stage, (H) metastasis, and (I) chemotherapy treatment in colon cancer patients. There is elevated expression of HIF-1α, MDR1 and LAPTM4B observed in metastatic, higher tumor stage and treatment naïve group compared to the non-metastatic, lower tumor stage and pre-treated group. Representative data were presented as mean ± SEM of triplicate experiments. Statistical significance was measured by Fisher’s Exact test (*p ≤ 0.05; **p ≤ 0.005).