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Distribution of integration sites in transduced human cord blood 10 days post vector exposure
| Vector | Unique RIS | Within genes | Within 50 kbp of TSS | In proto-oncogenes | Within 50 kbp of proto-oncogene TSS |
|---|---|---|---|---|---|
| FV-EGW-A1 | 5,133 | 44.6% | 51.2% | 8.3% | 7.9% |
| FV-SGW-A11 | 6,489 | 41.8% | 49.0% | 8.2% | 7.6% |
| FV-SGW1 | 1,594 | 43.0% | 53.5% | 8.8% | 7.9% |
data from Browning et al. 2017
RIS is retroviral integration sites, TSS is transcription start sites
