Table 2.
Parameter | N | 10 yr EFS % | P value | 10-yr PFS % | P value | 10 yr OS % | P value |
---|---|---|---|---|---|---|---|
Age | |||||||
≤ 35 years | 211 | 46.8 | 0.128 | 76 | 0.57 | 78.5 | 0.1 |
> 35 years | 232 | 40.3 | 74 | 73.5 | |||
Sokal risk group | |||||||
Low | 97 | 51.3 | 0.098 | 80 | 0.17 | 77.5 | 0.42 |
Intermediate/high | 346 | 40.6 | 74 | 75.5 | |||
Hasford score | |||||||
Low | 192 | 50.2 | 0.028 | 81 | 0.018 | 79.3 | 0.06 |
Intermediate/high | 251 | 37.6 | 71 | 73.1 | |||
EUTOS score | |||||||
Low | 379 | 43.6 | 0.62 | 77 | 0.009 | 76.3 | 0.48 |
High | 64 | 40.0 | 63 | 74.0 | |||
Adherence | |||||||
Adherent | 304 | 48.9 | 0.001 | 77 | 0.35 | 77.2 | 0.65 |
Non-adherent | 139 | 30.7 | 69 | 72.4 | |||
Prior treatment | |||||||
Absenta | 284 | 45.2 | 0.086 | 78 | 0.095 | 78.1 | 0.115 |
Present | 159 | 39.6 | 71 | 72.0 |
aUse of hydroxyurea up to 1 month before starting imatinib was considered as no prior therapy