Table 5.

PPARA haplotype frequencies and the association with risk of HA appetite loss.

Block	Haplotype	Freq (case)	Freq (control)	Pa	Crude		Adjustedb
					OR (95%CI)	P	OR (95%CI)	P
1	CT	0.868	0.803	0.035∗	1.00	–	1.00	–
	AC	0.112	0.173	0.035∗	0.61 (0.38 –0.98)	0.041∗	0.62 (0.39 –1.00)	0.050
	CC	0.020	0.024	0.764	0.77 (0.25–2.41)	0.660	0.78 (0.25–2.47)	0.680
2	AG	0.503	0.572	0.080	1.00	–	1.00	–
	AC	0.351	0.302	0.186	1.30 (0.93 –1.82)	0.120	1.32 (0.95 –1.86)	0.100
	GC	0.139	0.121	0.485	1.29 (0.79 –2.11)	0.310	1.34 (0.82 –2.20)	0.250

^aTwo-sided _X² test/Fisher’s exact tests. ^bAdjusted for age and SaO₂ in a logistic regression model. ^∗P < 0.05 indicates statistical significance. Block 1, contained rs7292407 and rs6520015 of PPARA; Block 2, contained rs4253623 and rs135538 of PPARA; Case, with appetite loss; Control, without appetite loss.