Table 1.
Lymphocytes profile of the patient at 21 years of age.
| Lymphocyte profile | % (/μL) | Reference value in adults |
|---|---|---|
| T CELL LINEAGES | ||
| T cells (CD3+/Lymphocytes) | (1,258) | 67.8 ± 5.4 (718–2,630) |
| Th cells (CD4+/CD3+) | 13.5 (170) | 59.9 ± 9.9 (407–1,550) |
| Tc cells (CD8+/CD3+) | 16.0 (201) | 34.1 ± 8.7 (210–1,140) |
| CD4+/CD8+ | 0.84 | 0.8–3.0 |
| Naïve Th cells (CD45RA+ CCR7+/CD3+CD4+) | 1.9 | 32.3 ± 24.0 |
| CD4+ TCM (CD45RA− CCR7+/CD3+CD4+) | 92.2 | 30.3 ± 18.7 |
| CD4+ TEM (CD45RA− CCR7−/CD3+CD4+) | 4.13 | 25.3 ± 16.1 |
| CD4+ TEMRA (CD45RA+ CCR7−/CD3+CD4+) | 1.75 | 12.1 ± 20.2 |
| Naïve Tc cells (CD45RA+ CCR7+/CD3+CD8+) | 13 | 40.1 ± 35.5 |
| CD8+ TCM (CD45RA− CCR7+/CD3+CD8+) | 71.9 | 20.8 ± 25.3 |
| CD8+ TEM (CD45RA− CCR7−/CD3+CD8+) | 7.2 | 19.7 ± 20.3 |
| CD8+ TEMRA (CD45RA+ CCR7−/CD3+CD8+) | 7.9 | 19.2 ± 25.8 |
| αβT cells (TCRαβ+TCRγδ−/CD3+) | 28.1 | 89.6 ± 4.8 |
| γδT cells (TCRαβ−TCRγδ+/CD3+) | 71.6 | 5.2 ± 4.2 |
| Double negative T cells (CD4− CD8−/CD3+TCRαβ+) | 0.83 | 0.77 ± 0.35 |
| Regulatory T cells (CD25+IL7R−/CD3+CD4+) | 9.16 | 3.11 ± 1.02 |
| Follicular helper T cells (CD45RO+CXCR5+/CD3+CD4+) | 3.06 | 7.02 ± 3.43 |
| Invariant natural killer T cells (Vb11+Va24+/CD3+) | 0.027 | 0.018 ± 0.012 |
| B CELL LINEAGES | ||
| B cells (CD19+/Lymphocytes) | 2.01 (44) | 12.2 ± 4.4 (110–627) |
| Transitional B cells (CD24+ CD38+/CD19+) | 2.2 | 8.1 ± 6.5 |
| Memory B cells (CD27+/CD19+) | 45.6 | 18.5 ± 8.2 |
| IgM memory B cells (CD27+ IgM+/CD19+) | 7.47 | 11.2 ± 4.0 |
| Switched memory B cells (CD27+ IgD−/CD19+) | 36.9 | 13.2 ± 7.2 |
| IgG memory B cells (CD27+ IgG+/CD19+) | 5.43 | 2.4 ± 1.4 |
| IgA memory B cells (CD27+ IgA+/CD19+) | 11.9 | 3.3 ± 2.8 |
| CD21+ B cells (CD20+/CD19+) | 79.7 | 14.3 ± 5.6 |
| Plasmablasts (CD38+ IgM−/CD19+) | 27.6 | 3.2 ± 2.3 |
| NK CELL LINEAGE | ||
| NK cells (CD16+ CD56+/Lymphocytes) | (732) | 13.4 ± 4.1 (82–760) |
Values above than the normal range are shown in red, and values below than the normal range are shown in blue. Th, helper T; Tc, cytotoxic T; TCM, central memory T; TEM, effector memory T; TEMRA, CD45RA+ effector memory T.