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. 2018 Dec 7;115(49):815–821. doi: 10.3238/arztebl.2018.0815

Table 2. Effect of perioperative or postoperative aromatherapy on anxiety, stress, pain, nausea, vomiting, and sleep quality*.

Year Intervention N Patients Surgery Type/quality Results
Symptom: Anxiety and stress
2013
(e58)
Bergamot oil vs.
placebo (diffuser)
109 Adults Ambulatory ‧‧surgery RCT, Q good Anxiety reduction: −3 vs. −2 pts (p = 0.02)
2014
(e65)
Postoperative
inhalation of
lavender vs. water
 60 Adults Cardiac surgery RCT, Q good Anxiety reduction: −6.13 vs. −5.27 pts (immediate),
−7.4 vs. 6.44 pts (3 rd postoperative day)
Symptom: Pain
2014
(e7)
Massage with
eucalyptus–lemon oil
vs. carrier oil vs.
standard
 60 Adults Vitrectomy RCT, Q good Pain reduction: shoulder, −1.1 vs. −0.8 vs. 0.15 FPS;
neck, −0.85 vs. −0.8 vs. 0.15 FPS; back, −0.75 vs. −0.6
vs. 0.3 FPS; waist, −0.9 vs. −1 vs. 0.1 FPS; arms, −0.85
vs. −0.05 vs. −0.05 FPS
Symptom: Nausea and vomiting
2018
(e1)
Perioperative inhalation of diverse aromatic oils vs. placebo 402 Mixed Mixed SR, Q high Nausea: SMD = −0.22 (95% CI: [−0.63; 0.18]; p = 0.28),
antiemetic reduction: RR = 0.60 (95% CI: [0.37; 0.97],
p = 0.04)
2016
(e37)
Inhalation of ginger/lavender/menthol vs. NaCl  80 Children
(4–16 years)
Ambulatory
surgery
RCT, Q good Reduction of retching: 90% vs. 78%;
reduction of antiemetics: 52% vs. 44%;
reduction of vomiting: 9% vs. 11%

* The complete table is available on the internet as eTable 2 CI, confidence interval; FPS, Faces Pain Scale; N, sample size; NaCl, sodium chloride saline solution; pts, points; Q, quality determined by AMSTAR score (for SR) or Jadad score (for RCT); RCT, randomized controlled trial; RR, relative risk; SMD, standardized mean difference; SR, systematic review