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. 2018 Dec 13;294(6):1891–1903. doi: 10.1074/jbc.RA118.006638

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© 2019 Sabrin et al.

Published under exclusive license by The American Society for Biochemistry and Molecular Biology, Inc.

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Figure 4. — Expression of genes encoding AmrAB-OprA and BpeEF-OprC efflux pumps in the presence of tetracycline. A and B, expression of amrB (BTH_I2444) in ΔemrBX and ΔostRX, respectively. C and D, expression of bpeF (BTH_II2105) in ΔemrBX and ΔostRX, respectively. Expression is reported relative to unsupplemented cultures. Asterisks represent statistically significant differences in expression compared with unsupplemented cultures based on Student's t test (*, p < 0.05; **, p < 0.001). Horizontal axes identify the concentration of tetracycline (in μg/ml). Note that the ordinate scale for A differs from that in B–D. Error bars, S.D.