Table 1.
Characteristics of studies included in this meta-analysis
| First Author and year | Country | Study population | sex | dose (g/day) | Duration (week) | Sample size | Mean age | Study design | Jadad score | Results |
|---|---|---|---|---|---|---|---|---|---|---|
| Japan | healthy subjects | M | 5.6 | 1 | 15 | 58 | p | 3 | SBP and DBP did not change significantly | |
| USA | healthy subjects | F | 6 | 8 | 23 | 58 | p | 3 | SBP and DBP decreased significantly | |
| Figueroa et al. 2009 | USA | healthy subjects | M | 6 | 4 | 17 | 22 | c | 3 | SBP and DBP did not change at rest after intervention |
| Figueroa et al. 2009 | USA | healthy subjects | M | 6 | 4 | 17 | 22 | c | 3 | SBP decreased significantly but DBP not changed significantly during CPT after intervention |
| Wong et al. 2015 ▶* | USA | healthy subjects | F | 6 | 8 | 27/41 | 58 | p | 3 | SBP and DBP decreased significantly |
| USA | healthy subjects | F | 6 | 2 | 13 | 70 | c | 4 | SBP and DBP did not change significantly. | |
| USA | healthy subjects | M | 6 | 2 | 12 | 71 | c | 4 | SBP did not change significantly. DBP decreased significantly | |
| Israel | healthy subjects | M | 6 | 2 | 16 | 24 | c | 4 | SBP and DBP did not change significantly | |
| USA | healthy subjects | M | 9 | 2 | 16 | 23 | c | 2 | SBP and DBP decreased significantly | |
| Munoz et al. 2012 | Mexico | Heart Failure | M/F | 3 | 17 | 34 | 67 | p | 2 | SBP and DBP did not change significantly |
SBP, systolic blood pressure; DBP, diastolic blood pressure, M: male, F: female, P: Parallel, C: crossover
*
Data of the two groups from three groups of the study by Wong et.al. 2015 were used for analysis. The total number of patients were 4 but 27 were analyzed.