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Summary of the binding capacity of Cdc42 mutants to effectors.
| CDC42 mutants | Effector binding | |||
|---|---|---|---|---|
| PAK1 | N-WASP | IQGAP1 | PAR6B | |
| L28 | ++++ | +++ | ++++ | ++ |
| A37 | - | +++ | + | - |
| K40 | + | - | +++ | - |
| H63 | + | ++++ | - | ++ |
| AA173-174 | ++++ | ++ | +++ | - |
| QQ186-187 | +++++ | +++++ | +++ | + |
+, binding to the indicated effectors; -, no binding activity; Li et al. (1999) and Guo et al. (2010).
