Table 1.

Experimental strategies, tools and conditions employed in the studies discussed.

RBP	Study	Mouse genotype	Cell type	LPS	Analytical strategy	Antibody	Data deposition
TTP	Stoecklin et al., 2008		RAW264.7 mouse macrophages	2 h,10 ng/ml LPS, E. coli 026:B6 (Sigma)	RIP-Chip Affymetrix Mouse Genome 430 2.0 array covering 39.000 transcripts	Rabbit anti-TTP	doi: 10.1074/jbc.M709657200
	Kratochvill et al., 2011	C57BL/6 mice TTP(wt) and TTP(-/-)	BMDM	3 h, 10 ng/ml LPS, E. coli 055:B5 (Sigma)	RIP-Chip Affymetrix Mouse Gene ST 1.0 array covering 28 853 genes	Rabbit anti-TTP (Schaljo et al., 2009)	http://www.ncbi.nlm.nih.gov/geo/acc. GSE28880.
	Tiedje et al., 2016	C57BL/6 TTP(-/-) mice expr. GFP-TTP(wt) and GFP-TTP(S52,178A)	BMDM	1 h, 1 μg/μl LPS	iCLIP	GFP-nanobodies	http://www.ncbi.nlm.nih.gov/geo/acc. GSE81250 TTP-atlas: http://ttp-atlas.univie.ac.at
	Sedlyarov et al., 2016	C57BL/6 mice TTP(wt) and TTP(ΔM)	BMDM	3 h, 6 h, 10 ng/ml LPS (Sigma)	PAR-iCLIP	Rabbit anti-TTP (Kratochvill et al., 2011)	http://www.ncbi.nlm.nih.gov/geo/acc. GSE63468 TTP-atlas: http://ttp-atlas.univie.ac.at
HUR	Sedlyarov et al., 2016	C57BL/6 mice TTP(wt) and TTP(ΔM)	BMDM	3 h, 6 h, 10 ng/ml LPS (Sigma)	PAR-iCLIP	HUR, clone 3A2 (Thermo Fisher Sci.)	http://www.ncbi.nlm.nih.gov/geo/acc. GSE63468 TTP-atlas: http://ttp-atlas.univie.ac.at
TIAR	Kharraz et al., 2016		RAW264.7, expr. TIAR- or TIAR-ΔRRM-FLAG	2 h, 100 ng/ml LPS, E. coli 0127:B8 (Sigma)	RIP-Chip Mouse Exonic Evidence Based Oligonucleotide (MEEBO) array covering 38.784 70mer probes (Stanford University, United States)	Anti-FLAG M2 agarose (Sigma)	http://www.ncbi.nlm.nih.gov/geo/acc.GSE77577
hnRNP K	Liepelt et al., 2014		RAW264.7 mouse macrophages	6 h, 10 ng/ml LPS, E. coli 0111:B4 (Sigma)	RIP-Chip Affymetrix Mouse Genome 430 2.0 array covering 39.000 transcripts	monoclonal hnRNP K (Naarmann et al., 2008)	http://www.ncbi.nlm.nih.gov/geo/acc.GSE48463

Information related to experimental tools and conditions as provided in the original papers.