Table 1.

Clinical characteristics of 11 subjects with the ‘hot cross bun’ sign

ID	Sex	Age at onset (years)	Current age (years)	Time to MRI (years after symptom onset)	Parkinsonism	Cerebellar signs	Urinary symptoms	Erectile dysfunction	Orthostasis	Levodopa response	Diagnosis
1	M	55	60	2	Yes	Yes	Frequency	Not documented	Not documented	No	Possible MSA
2	F	59	Dead at 71	9	No	Yes	Incontinence	N/A	Not documented	N/A	Uncertain after autopsy
3	M	60	65	5	Yes	No	None	No	No	No	Probable DLB
4	M	61	66	3	Yes	No	Retention	Yes	Yes	Yes	Possible MSA
5	F	36	40	2	No	Yes	Urgency	N/A	Yes	N/A	Undefined hereditary ataxia
6	F	58	69	8	No	Yes	Incontinence	N/A	No	No	Probable MSA
7	F	55	68	3	No	Yes	Incontinence	N/A	Yes	N/A	Probable MSA
8	F	53	Dead at 65	4	Yes	Yes	Incontinence and retention	N/A	Yes	No	Probable MSA
9	F	66	68	0	Yes	Yes	Incontinence	N/A	No	Yes	Probable MSA
10	M	33	79	33	No	Yes	None	Not documented	Not documented	N/A	Undefined hereditary ataxia
11	M	30	68	36	No	Yes	None	Yes	Not documented	N/A	Undefined hereditary ataxia

MSA: multiple system atrophy, DLB: dementia with Lewy bodies.