Table 1.
Baseline features of patients with end-stage renal disease due to granulomatosis with polyangiitis (ESRD-GPA)
| GPA-ESRD | Waitlisted | Transplanted during study period | |
|---|---|---|---|
| N | 5929 | 1525 | 946 |
| Age at ESRD, years (%) | |||
| <40 | 12.6% | 27.9% | 33.9% |
| 40–49 | 9.9% | 18.2% | 19.2% |
| 50–59 | 16.9% | 26.6% | 24.4% |
| ≥60 | 60.6% | 27.3% | 22.4% |
| Male (N, %) | 3367 (57%) | 906 (59%) | 560 (59%) |
| Body mass index | 26.8 (±6.7) | 27.0 (±6.5) | 26.7 (±6.4) |
| Race | |||
| White | 5305 (90%) | 1312 (86%) | 825 (87%) |
| Black | 385 (7%) | 132 (9%) | 72 (8%) |
| Other | 239 (4%) | 81 (5%) | 51 (5%) |
| Hispanic | 536 (9%) | 191 (13%) | 106 (11%) |
| Comorbidities | |||
| Diabetes | 852 (14%) | 134 (9%) | 68 (7%) |
| Hypertension | 4014 (68%) | 1010 (67%) | 602 (64%) |
| COPD | 507 (9%) | 48 (3%) | 20 (2%) |
| CAD | 686 (12%) | 67 (5%) | 42 (5%) |
| PVD | 303 (5%) | 35 (2%) | 21 (2%) |
| CHF | 859 (15%) | 94 (6%) | 43 (5%) |
| CVA | 265 (5%) | 36 (2%) | 24 (3%) |
| Other cardiac disease | 151 (3%) | 20 (2%) | 16 (2%) |
| Tobacco | 227 (4%) | 48 (3%) | 20 (2%) |
| Cancer | 306 (5%) | 38 (3%) | 20 (2%) |
| Comorbidity score | 1.1 (±1.8) | 0.5 (±1.2) | 0.4 (±1.1) |
| First modality | |||
| Transplant* | 128 (2%) | - | - |
| Haemodialysis | 5328 (90%) | 1305 (86%) | 798 (84%) |
| Peritoneal dialysis | 450 (8%) | 220 (14%) | 148 (16%) |
*
Patients transplanted prior to dialysis were excluded from the transplantation analyses.
CAD, coronary artery disease; CHF, congestive heart failure; COPD, chronic obstructive pulmonary disease; CVA, cerebrovascular attack; MPA, microscopic polyangiitis; PVD, peripheral vascular disease.