Murine FSHR SynCon Vaccine Generates Strong CD8 and CD4 Responses
(A and C) Percentages of IFNγ, TNF-α, and IL-2 produced by (A) CD8+ or (C) CD4+ T cells from the spleen of mice immunized with murine FSHR SynCon vaccine, murine native FSHR, or pVAX stimulated with native murine FSHR peptides. (B and D) Pie charts representing the cytokines produced by (B) CD8 and (D) CD4 T cells of each of the groups. The pie size corresponds to the number of responding T cells (n = 5 mice per group). ANOVA. Error bars represent SEM. *p < 0.05, **p < 0.01, ***p < 0.001.