Table 5.
SNP allele frequencies and associations for the top 3 SNPs in subgroup analysis of mild/moderate/severe PACG cases versus controls.
| SNP | CHR | MA | MAF control | Mild (N = 22) | Moderate (N = 10) | Severe (N = 19) | ||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MAF | P | OR (95% CI) | MAF | P | OR (95% CI) | MAF | P | OR (95% CI) | ||||
| rs1676486 | 1 | A | 0.19 | 0.2 | 0.797 | 1.098 (0.540–2.233) | 0.45 | 0.018 | 2.416 (1.284–4.544) | 0.39 | 0.011 | 2.119 (1.204–3.729) |
| rs3753841 | 1 | G | 0.26 | 0.23 | 0.722 | 0.892 (0.471–1.687) | 0.55 | 0.009 | 2.158 (1.287–3.618) | 0.5 | 0.006 | 1.962 (1.239–3.106) |
| rs12138977 | 1 | C | 0.18 | 0.14 | 0.549 | 0.773 (0.329–1.814) | 0.45 | 0.007 | 2.550 (1.344–4.839) | 0.45 | 0.001 | 2.535 (1.465–4.386) |
Chi-square tests and logistic regression were used.