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. Author manuscript; available in PMC: 2019 Feb 11.
Published in final edited form as: Dev Cell. 2016 Feb 22;36(4):356–357. doi: 10.1016/j.devcel.2016.02.002

Figure 1. Different Transcriptional States Are Associated with Distinct 3D Organization of Chromatin.

Figure 1.

(A) Transcriptionally active chromatin domains are less condensed than inactive or repressed domains and become less dense with increasing domain length. Repressed chromatin shows a reverse behavior, with longer domains becoming more condensed.

(B) Active domains frequently intermingle with other active and inactive domains, whereas Polycomb-repressed regions are spatially isolated from all other domains.