Skip to main content
. Author manuscript; available in PMC: 2019 Feb 11.
Published in final edited form as: Clin Radiol. 2015 Jul 29;70(11):1165–1176. doi: 10.1016/j.crad.2015.06.093

Figure 1.

Figure 1

Importance of clinical context. A 60-year-old man referred for raised PSA. (a) Axial T2WI demonstrates a focal lesion in the left mid PZ (arrows), with matching restricted diffusion (b); PI-RADS score 4. Subsequent transperineal fused TRUS-MRI targeted-biopsy is planned (c), with sagittal US image confirming needle placement in the lesion (d). Histology confirms high-grade PIN. MRI repeated at 18 months shows no change in the previously sampled lesion (e, f). Although the PI-RADS score is based solely on mpMRI findings and remains 4, when taking account of clinical context, the report conclusion would more appropriately state that clinically significant cancer is unlikely to be present.