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. 2019 Feb 11;7:17. doi: 10.1186/s40478-019-0671-0

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© The Author(s). 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 5 — Electron micrographs illustrating the presence of FITC-albumin-related DAB-positive endothelial vesicles (arrow heads) and caveolae (arrows), which became apparent from 1 h to 4 h of pMCAO and in 4 h tMCAO after ischemia induction. Here, caveolae as well as vesicles were regularly detected in endothelial cells showing an endothelial edema (score 1). Inset: contralateral non-affected vessel. L = vascular lumen; scale bars: each 1 μm