Table 1.
Evidence for the effectiveness of anti-hypertensive drugs in NRDL of UEBMI——From the international evidence-based drug list
| Dosage form | JNC 8 | NICE 2011 | WHO EML 2017 | Frequency of inclusion | |
|---|---|---|---|---|---|
| Calcium antagonist | |||||
| Class A | |||||
| Amlodipine | oral release dosage form | √ | √ | √ | 3 |
| Nimodipine | oral release dosage form | – | – | – | 0 |
| Nitrendipine | oral release dosage form | – | – | – | 0 |
| Nifedipine | oral release dosage form | – | √ | √ | 2 |
| Diltiazem | oral release dosage form | – | √ | √ | 2 |
| Verapamil | oral release dosage form | – | √ | √ | 2 |
| Verapamil | injection | – | – | √ | 1 |
| Class B | |||||
| L - nmda amlodipine | oral release dosage form | – | – | – | 0 |
| Amlodipine atorvastatin calcium | oral release dosage form | – | – | – | 0 |
| Benidipine | oral release dosage form | – | – | – | 0 |
| Felodipine | oral release dosage form, controlled release dosage form | – | √ | – | 1 |
| Felodipine II | controlled release dosage form | – | √ | – | 1 |
| Lacidipine | oral release dosage form | – | √ | – | 1 |
| Lercanidipine | oral release dosage form | – | √ | – | 1 |
| Nicardipine | oral release dosage form, controlled release dosage form | – | – | – | 0 |
| Nicardipine | injection | – | – | – | 0 |
| Nimodipine | injection | – | – | – | 0 |
| Nitrendipine and Atenolol | oral release dosage form | – | – | – | 0 |
| Cilnidipine | oral release dosage form | – | – | – | 0 |
| Nifedipine (I,II,III) | controlled release dosage form | – | √ | √ | 2 |
| Levamlodipine besylate tablets | oral release dosage form | – | √ | – | 1 |
| Diltiazem | injection | – | – | – | 0 |
| Diltiazem (II) | controlled release dosage form | – | √ | √ | 2 |
| Verapamil | controlled release dosage form | – | √ | √ | 2 |
| β blockers | |||||
| Class A | |||||
| Propranolol | oral release dosage form | – | √ | √ | 2 |
| Atenolol | oral release dosage form | √ | √ | – | 2 |
| Bisoprolol | oral release dosage form | – | √ | √ | 2 |
| Metoprolol | oral release dosage form | √ | √ | – | 2 |
| Metoprolol | injection | – | – | – | 0 |
| Class B | |||||
| Propranolol | Sustained or controlled release dosage form | – | √ | √ | 2 |
| Propranolol | injection | – | – | – | 0 |
| Sotalol | oral release dosage form | – | √ | – | 1 |
| Sotalol | injection | – | – | – | 0 |
| Esmolol | injection | – | – | – | 0 |
| Metoprolol | controlled release dosage form | √ | √ | – | 2 |
| Arotinolol | oral release dosage form | – | – | – | 0 |
| Carvedilol | oral release dosage form | – | – | – | 0 |
| Labetalol | oral release dosage form | – | – | – | 0 |
| diuretics | |||||
| Class A | |||||
| Hydrochlorthiazide | oral release dosage form | √ | √ | √ | 3 |
| Indapamide | oral release dosage form, controlled release dosage form | √ | √ | – | 2 |
| Furosemide | oral release dosage form | – | – | √ | 1 |
| Furosemide | injection | – | – | √ | 1 |
| Triamterene | oral release dosage form | – | – | – | 0 |
| Spironolactone | oral release dosage form | – | √ | √ | 2 |
| Class B | |||||
| Bumetanide | oral release dosage form | – | – | – | 0 |
| Bumetanide | injection | – | – | – | 0 |
| Torasemide | oral release dosage form | – | – | – | 0 |
| Torasemide | injection | – | – | – | 0 |
| Amiloride | oral release dosage form | – | √ | √ | 2 |
| ACEIs | |||||
| Class A | |||||
| Captopril | oral release dosage form | √ | √ | – | 2 |
| Enalapril | oral release dosage form | √ | √ | √ | 3 |
| Class B | |||||
| Benazepril | oral release dosage form | – | – | – | 0 |
| Fosinopril | oral release dosage form | – | – | – | 0 |
| Lisinopril | oral release dosage form | √ | √ | – | 2 |
| Ramipril | oral release dosage form | – | √ | – | 1 |
| Imidapril | oral release dosage form | – | – | – | 0 |
| Perindopril | oral release dosage form | – | √ | – | 1 |
| Cilazapril | oral release dosage form | – | – | – | 0 |
| Amlodipine benapril I (II) | oral release dosage form | – | – | – | 0 |
| Benapril hydrochlorothiazide | oral release dosage form | – | – | – | 0 |
| compound captopril | oral release dosage form | – | – | – | 0 |
| Lynopli hydrochlorothiazide | oral release dosage form | – | – | – | 0 |
| Enalpril hydrochlorothiazide | oral release dosage form | – | – | – | 0 |
| Enopril folic acid | oral release dosage form | – | – | – | 0 |
| Angiotensin II receptor antagonist | |||||
| Class B | |||||
| Olmesartan Medoxomil | oral release dosage form | – | – | – | 0 |
| Irbesartan | oral release dosage form, controlled release dosage form | √ | √ | – | 2 |
| Candesartan | oral release dosage form | √ | √ | – | 2 |
| Losartan | oral release dosage form | √ | √ | √ | 3 |
| Telmisartan | oral release dosage form | √ | √ | – | 2 |
| Valsartan | oral release dosage form | √ | √ | – | 2 |
| Omethane hydrochlorothiazide | oral release dosage form | – | – | – | 0 |
| irbesartan hydrochlorothiazide | oral release dosage form | – | – | – | 0 |
| chlorothiazide | oral release dosage form | – | – | – | 0 |
| Timisaltan hydrochlorothiazide | oral release dosage form | – | – | – | 0 |
| Valsartan chlordipine I (II) | oral release dosage form | – | – | – | 0 |
| Valsartan hydrochlorothiazide | oral release dosage form | – | – | – | 0 |
| vasodilators | |||||
| Class A | |||||
| Phentolamine | injection | – | – | – | 0 |
| Sodium nitroprusside | injection | – | – | √ | 1 |
| Class B | |||||
| Phenoxybenzamine | oral release dosage form | – | – | – | 0 |
| Phenoxybenzamine | injection | – | – | – | 0 |
| Hydralazine | oral release dosage form | – | – | √ | 1 |
| Hydralazine | injection | – | – | √ | 1 |
| Minoxidil | oral release dosage form | – | – | – | 0 |
| Others | |||||
| Class A | |||||
| Reserpine | injection | – | – | – | 0 |
| Prazosin | oral release dosage form | – | √ | – | 1 |
| Compound reserpine | oral release dosage form | – | – | – | 0 |
| Compound reserpine ammonia benzene pteridine | oral release dosage form | – | – | – | 0 |
| Class B | |||||
| Dibazole | oral release dosage form | – | – | – | 0 |
| Methyldopa | oral release dosage form | – | √ | √ | 2 |
| Clonidine | oral release dosage form | – | – | – | 0 |
| Clonidine | Patch | – | – | – | 0 |
| Reserpine | oral release dosage form | – | – | – | 0 |
| Ligustrazine | Injection | – | – | – | 0 |
| Doxazosin | oral release dosage form, controlled release dosage form | – | √ | – | 1 |
| Naftopidil | oral release dosage form | – | – | – | 0 |
| Urapidil | oral release dosage form, controlled release dosage form | – | – | – | 0 |
| Urapidil | injection | – | – | – | 0 |