Figure 8.

Assessment of lncITPF Value in IPF Patients and Its Regulatory Mechanism

(A) Expression levels of lncITPF increased in 76 patients with IPF, as detected by qRT-PCR. Normal samples corresponding to the sex and age of patients with IPF were selected. (B) Negative correlation between lncITPF and FVC analyzed through Pearson’s correlation. (C) lncITPF expression increased with age. This population comprised a group of healthy volunteers. (D) ROC curve of lncITPF shows that the sensitivity and specificity values are 64.3 and 95, respectively, in IPF patients. (E) Regulatory mechanism of lncITPF. Each bar represents the mean ± SD; *p < 0.05, **p < 0.01, and ***p < 0.001.