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. 2019 Jan 18;116(6):2220–2225. doi: 10.1073/pnas.1818539116

Fig. 5.

Fig. 5.

Decrease in KIT expression on HHT treatment in accordance with down-regulation of MYC expression. (A) mRNA (Left and Middle) and protein (Right) expression levels of MYC and KIT in Kasumi-1 and SKNO-1 cells treated with HHT for 24 h. (B) CD117 fluorescence intensity in shSCR- and shNKRF- transfected Kasumi-1 cells treated with HHT for 24 h. (C) Life span of the mice xenografted with shSCR- or shNKRF-transfected Kasumi-1 cells (Left) and SKNO-1 cells (Right) and treated with HHT or vehicle control. CON, control. Data are mean ± SEM of three independent experiments. ns, P > 0.05; *P < 0.05; **P < 0.01; ***P < 0.001.