Table 4. The mean, SD and p-value of T subsets among healthy volunteers, 1-year and 5-year renal allograft recipients.
Mean ± SD | p-value | |||||
---|---|---|---|---|---|---|
Healthy (H) | 1-year (1y) | 5-year (5y) | H vs 1y | H vs 5y | 1y vs 5y | |
CD3+ | 72.08 ± 7.07 | 67.65 ± 11.07 | 62.88 ± 14.62 | 0.0302 | 0.0005 | 0.0796 |
CD4+ | 38.77 ± 7.89 | 35.73 ± 11.15 | 35.03 ± 10.91 | 0.1484 | 0.0791 | 0.7687 |
CD8+ | 32.63 ± 6.97 | 34.64 ± 8.72 | 33.15 ± 9.88 | 0.2410 | 0.7829 | 0.4559 |
CD3+HLA-DR+ | 55.38 ± 19.77 | 51.37 ± 11.91 | 49.28 ± 16.09 | 0.2457 | 0.1291 | 0.4858 |
αβ | 85.22 ± 11.41 | 90.46 ± 6.09 | 91.25 ± 6.16 | 0.0076 | 0.0038 | 0.5474 |
γδ | 14.20 ± 11.39 | 8.99 ± 5.82 | 8.04 ± 6.04 | 0.0072 | 0.003 | 0.4577 |
Vδ1 γδ | 17.28 ± 17.87 | 35.47 ± 16.22 | 35.81 ± 23.13 | <0.0001 | 0.0001 | 0.9354 |
Vδ2 γδ | 73.96 ± 22.10 | 43.96 ± 22.13 | 46.52 ± 28.61 | <0.0001 | <0.0001 | 0.6374 |
CD4+ CD57+ | 3.77 ± 2.76 | 8.34 ± 8.44 | 4.31 ± 3.63 | 0.0014 | 0.4540 | 0.0057 |
CD4+ PD1+ | 32.36 ± 9.09 | 38.47 ± 12.87 | 38.60 ± 15.89 | 0.0105 | 0.0271 | 0.9652 |
CD8+ CD57+ | 36.71 ± 13.36 | 41.20 ± 13.44 | 42.59 ± 14.90 | 0.1212 | 0.0636 | 0.6453 |
CD8+ PD1+ | 25.60 ± 8.81 | 34.17 ± 13.50 | 32.34 ± 13.25 | 0.0008 | 0.0082 | 0.9240 |
CD4+ CD28+CD27+ | 86.59 ± 4.63 | 74.31 ± 11.74 | 82.92 ± 7.44 | <0.0001 | 0.0088 | 0.0001 |
CD4+ CD28-CD27- | 5.22 ± 2.73 | 15.01 ± 9.85 | 7.15 ± 7.11 | <0.0001 | 0.1073 | <0.0001 |
CD8+ CD28+CD27+ | 50.02 ± 13.34 | 36.21 ± 12.61 | 34.53 ± 14.48 | <0.0001 | <0.0001 | 0.5620 |
CD8+ CD28-CD27- | 34.74 ± 12.13 | 47.64 ± 12.60 | 52.32 ± 15.63 | <0.0001 | <0.0001 | 0.1238 |
CD4+ CM T | 45.53 ± 8.38 | 40.13 ± 12.96 | 56.23 ± 10.87 | 0.0250 | <0.0001 | <0.0001 |
CD4+ EM T | 15.02 ± 4.82 | 25.74 ± 15.14 | 22.76 ± 10.40 | <0.0001 | <0.0001 | 0.2933 |
CD8+ CM T | 7.56 ± 3.66 | 4.93 ± 4.59 | 5.71 ± 4.29 | 0.0043 | 0.0394 | 0.4157 |
CD8+ EM T | 31.37 ± 9.86 | 28.17 ± 12.71 | 26.07 ± 13.08 | 0.1945 | 0.0415 | 0.4489 |