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. 2019 Feb 7;11:1221–1230. doi: 10.2147/CMAR.S188046

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© 2019 Deng et al. This work is published and licensed by Dove Medical Press Limited

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Positive immunostaining was predominantly localized in the cytoplasm.

Notes: Low levels of nuclear staining were also evident in some cancer cells. (A) H&E staining in ccRCC tissue. Scale bar, 20 µm. (B) Some scattered Nrf2 nucleus-positive cells were observed in ccRCC tissue (shown by black arrows, scale bar, 20 µm). (C) Some scattered HO-1 nucleus-positive cells were observed in ccRCC tissue (shown by black arrows, scale bar, 20 µm).

Abbreviation: ccRCC, clear cell renal cell carcinoma.