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. 2019 Feb 7;11:1221–1230. doi: 10.2147/CMAR.S188046

Table 2.

Correlation analysis between Nrf2/HO-1 protein expression and clinicopathological parameters

Clinical indexes n Nrf2 positive (%) P-value n HO-1 positive (%) P-value
Age (years)
 <53 87 69 (79.3) 0.724 80 70 (87.5) 0.470
 ≥53 65 50 (76.9) 53 44 (83.0)
Gender
 Male 103 82 (79.6) 0.566 91 78 (85.7) 1.000
 Female 49 37 (75.5) 42 36 (85.7)
ISUP grade
 1 13 8 (61.5) 0.298 13 9 (69.2) 0.303
 2 54 44 (81.5) 49 43 (87.8)
 3 65 53 (81.5) 54 48 (88.9)
 4 20 14 (70.0) 17 14 (82.4)
Tumor size (cm)
 <9 137 104 (75.9) 0.042* 121 102 (84.3) 0.214
 ≥9 15 15 (100) 12 12 (100)
T staging
 T1–T2 134 108 (80.6) 0.060 119 101 (84.9) 0.684
 T3–T4 18 11 (61.1) 14 13 (92.9)
Sarcomatoid differentiation
 No 132 105 (79.5) 0.335 116 100 (86.2) 0.958
 Yes 20 14 (70.0) 17 14 (82.4)
Lymph node metastasis
 No 149 118 (79.2) 0.230 130 112 (86.2) 0.905
 Yes 3 1 (33.3) 3 2 (66.7)

Note:

*

P<0.05.

Abbreviation: ISUP, International Society of Urological Pathology.