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. 2019 Feb 7;11:1211–1220. doi: 10.2147/CMAR.S184368

Figure 8.

Figure 8

The effect of KCNJ15 overexpression on the PI3K/AKT, EMT, and MMP-7 pathways.

Notes: (A) Western blot analysis was performed to examine the expression of P-mTOR, mTOR, PI3K, P-GSK-3β, GSK-3β, and p21 in Caki-2 and OS-RC-2 cell lines. (B) The expression of EMT-associated proteins (N-cadherin and vimentin) and MMP-7 was determined by Western blot.

Abbreviations: EMT, epithelial–mesenchymal transition; GSK, glycogen synthase kinase; MMP, matrix metalloproteinase; mTOR, mechanistic target of rapamycin; PI3K, phosphoinositide 3-kinase.