Table 7.

Test Characteristics of Clinical Assessment Alone vs. POCUS Guidance in Pediatric SSTI Management

	Sensitivity, % (95% CI)	Specificity, % (95% CI)	+LR (95% CI)	−LR (95% CI)
All (n = 305)
Clinical assessment only	76.2 (60.2–87.4)	93.9 (82.1–98.4)	12.4 (4.1–37.7)	0.25(0.15–0.44)
POCUS guidance	90.3 (83.4–94.7)	80.0 (70.0–87.4)	4.5 (2.98–6.85)	0.12 (0.07–0.21)
High certainty cases* (n = 183)
Clinical assessment only	79.3 (59.7–91.3)	94.9(81.4–99.1)	15.5 (4.0–60.4)	0.22 (0.11–0.44)
POCUS guidance	89.9 (79.6–95.5)	73.9 (58.6–85.2)	3.4 (2.10–5.64)	0.14(0.07–0.28)
Equivocal casest† (n = 122)
Clinical assessment only	69.2 (38.9–89.6)	90.0 (54.1–99.5)	6.9 (1.0–46.0)	0.34(0.15–0.79)
POCUS guidance	90.9 (79.2–96.6)	86.3 (72.0–94.3)	6.7 (3.2–14.1)	0.11 (0.05–0.24)

POCUS = point-of-care ultrasound; SSTI = skin and soft tissue infection; CI = confidence interval; +LR = positive likelihood ratio; −LR = negative likelihood ratio.

^*Clinical suspicion of drainable fluid collection 0–20 or 81–100 on visual analog scale.

^†Clinical suspicion of drainable fluid collection 21–80 on visual analog scale.