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. Author manuscript; available in PMC: 2020 Feb 15.
Published in final edited form as: J Immunol. 2019 Jan 16;202(4):1229–1238. doi: 10.4049/jimmunol.1801227

Figure. 8: Model for the possible mode of action of AG-30/5C on host defense and wound healing.

Figure. 8:

We propose that in addition to its direct antimicrobial activity, AG-30/5C contributed to host defense via MC degranulation through MRGPRX2. AG-30/5C contributes to wound healing via its action on vascular endothelial cells keratinocyte proliferation and migration through MRGPRX3 and MRGPRX4.