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High-mobility group box 1 (HMGB1) mRNA expression in colorectal cancer. (A) HMGB1 mRNA expression was nearly 2.4-fold higher in the cancer tissues (P < .05). (B) Higher HMGB1 expression in Duke stage A-B and Duke stage C-D cancer tissues compared to the normal tissues (P < .05) was observed, but there was no significant difference between the Duke stage A-B and Dukes stage C-D groups (P > .05).
