Table 4.
Univariate and multivariate regression of aortic valve weight (r2 = 0.37)
| Valve weight (g), univariate
analysis |
Multivariate analysis |
|||||
|---|---|---|---|---|---|---|
| Term | Yes | No | P-value | Term | Estimate | P-value |
| Male | 3.1 ± 1.3 | 1.9 ± 0.9 | <0.0001 | Male | 0.34 | <0.0001 |
| Age >70 | 2.5 ± 1.2 | 3.0 ± 1.4 | <0.0001 | Age (per decade)a | 0.08 | 0.05 |
| Bicuspid valve | 3.4 ± 1.5 | 2.4 ± 1.1 | <0.0001 | Bicuspid valve | 0.35 | <0.0001 |
| Cigarette smoker | 3.3 ± 1.5 | 2.6 ± 1.3 | 0.003 | Cigarette smoker | 0.21 | 0.007 |
| Diabetes | 2.4 ± 1.1 | 2.8 ± 1.3 | <0.0001 | Diabetes | −0.11 | 0.004 |
| Hypertension | 2.5 ± 1.2 | 3.1 ± 1.5 | <0.0001 | Hypertension | −0.09 | 0.03 |
| Dyslipidaemia | 2.6 ± 1.3 | 2.9 ± 1.5 | 0.03 | Dyslipidaemia | −0.10 | 0.07 |
| CAD | 2.6 ± 1.2 | 2.8 ± 1.4 | 0.02 | CAD | 0.04 | 0.31 |
| Dialysis | 2.2 ± 1.2 | 2.6 ± 1.3 | 0.36 | |||
| LVOT diameter ≥2.3 cm | 3.2 ± 1.3 | 2.1 ± 1.0 | <0.0001 | LVOT diametera (per mm increase) | 0.21 | <0.0001 |
| BSA >2.0 | 3.1 ± 1.3 | 2.3 ± 1.2 | <0.0001 | |||
CAD, coronary artery disease; LVOT, left ventricular outflow tract; BSA, body surface area.
aIncluded as a continuous variable in the multivariate analysis.