FSTL1 enhances multiple drug resistance in breast cancer cells. (a) FSTL1 protein expression in MDA-MB-231, MDA-MB-468 and HCC38 cells transfected with control vector or FSTL1 plasmids by western blot. (b, c) Cell LIVE/DEAD assays in FSTL1 overexpression MDA-MB-231, MDA-MB-468 and HCC38 cells treated with CDDP (b) or DOX (c), respectively. *p < 0.05. (d, e) Cell viability in FSTL1 overexpression MDA-MB-231, MDA-MB-468 and HCC38 cells treated with different doses of CDDP (d) or DOX (e) indicated, respectively. (f, g) Colony formation in FSTL1 overexpression MDA-MB-231, MDA-MB-468 and HCC38 cells treated with different doses of CDDP (f) or DOX (g) indicated, respectively. *p < 0.05.