Table 2.
AUROC, sensitivity, specificity and positive predictive value obtained when discerning lesions from contralateral NAWM and from controls using a logistic classifier trained within a 10-fold cross-validation procedure.
| Performance (LESION/CLNAWM) |
|||||
|---|---|---|---|---|---|
| FA | MD | AD | RD | FR | |
| AUROC | 0.75 | 0.85 | 0.70 | 0.85 | 0.90 |
| Sensitivity | 0.79/0.70 | 0.79/0.75 | 0.70/0.67 | 0.79/0.75 | 0.79/0.79 |
| Specificity | 0.71/0.80 | 0.75/0.79 | 0.67/0.71 | 0.75/0.79 | 0.80/0.80 |
| Positive Predictive value | 0.73/0.77 | 0.76/0.78 | 0.68/0.69 | 0.76/0.78 | 0.79/0.79 |
Abbreviations: AUROC = Area under Receiver Operating Characteristic curve; NAWM = Normal-Appearing White Matter; FA = Fractional Anisotropy; MD = Mean Diffusivity; AD = Axial Diffusivity; RD = Radial Diffusivity; FR = Restricted Fraction.