Table 1.
The 11 potential synergistic drug combinations predicted by SyFFM and 9 are confirmed by literature.
| Drug 1 | Drug 2 | Evidence of synergy combinations |
|---|---|---|
| ampicillin sodium | tazobactam | PMID:24041466 |
| esomeprazole magnesium | sodium bicarbonate | None |
| trandolapril | hydrochlorothiazide | PMID: 7527107 |
| dienogest | ethinyl estradiol | PMID: 20394455 |
| eprosartan mesylate | amlodipine besylate | None |
| tenofovir disoproxil fumarate | lamivudine | PMID:13130407 |
| niacin | atorvastatin calcium | PMID:10095800 |
| trandolapril | amlodipine besylate | None |
| norelgestromin | Ethinyl Estradiol | PMID: 11849630 |
| Ethinyl estradiol | ethynodiol diacetate | PMID: 2046084 |
| desogestrel | Ethinyl estradiol | PMID: 9673846 |