Table 2.
NoR
n = 20 |
R
n = 15 |
p-value* | |
---|---|---|---|
CHARACTERISTICS AT TIME OF TRANSPLANTATION | |||
Recipient | |||
Age at transplantation (years) | 53 ± 13 | 51 ± 16 | 0.74 |
Origin of renal disease, n (%) | 0.80 | ||
Glomerulonephritis | 1 (5) | 3 (20) | |
Diabetes mellitus | 3 (15) | 2 (13) | |
Vascular | 6 (30) | 4 (27) | |
Genetic | 4 (20) | 3 (20) | |
Uropathy | 1 (5) | 1 (7) | |
Undetermined | 5 (25) | 2 (13) | |
Duration of dialysis (months) | 21 ± 20 | 31 ± 43 | 0.83 |
DONOR | |||
Donor age (years) | 50 ± 14 | 48 ± 17 | 0.71 |
Donor sex, men, n (%) | 14 (70) | 11 (73) | 1.0 |
Deceased donor, n (%) | 17 (85) | 14 (93) | 0.69 |
Extended criteria donor, n (%) | 6 (30) | 7 (47) | 0.48 |
TRANSPLANTATION | |||
Number of HLA-A, B, C, DR, DQ mismatches | 6.1 ± 1.5 | 5.2 ± 1.9 | 0.17 |
Combined kidney-pancreas transplantation, n (%) | 2 (10) | 1 (7) | 1.00 |
Cold ischemia time (min) | 677 ± 414 | 806 ± 490 | 0.40 |
Delayed graft function, n (%) | 0 (0) | 3 (21) | 0.06 |
CHARACTERISTICS AT TIME OF VACCINATION | |||
Time elapsed since transplantation (months) | 23 ± 19 | 24 ± 15 | 0.77 |
IMMUNOSUPPRESSION | |||
Induction therapy | |||
Thymoglobuline, n (%) | 17 (85) | 9 (60) | 0.12 |
Maintenance regimen | |||
Tacrolimus, n (%) | 19 (95) | 10 (67) | 0.06 |
Ciclosporin, n (%) | 1 (5) | 5 (33) | |
mTOR-Inhibitors, n (%) | 2 (10) | 1 (7) | 1.00 |
Mycophenolate, n (%) | 18 (90) | 14 (93) | 1.00 |
Azathioprin, n (%) | 1 (5) | 0 | |
Prednisone, n (%) | 12 (60) | 12 (80) | 0.28 |
GRAFT FUNCTION | |||
eGFR (ml/min/m2) | 59 ± 22 | 61 ± 23 | 0.78 |
Proteinuria**, n (%) | 3 (15) | 3 (20) | 1.00 |
Unpaired t-test was used for comparison of continuous variables and Fisher's exact test was used for comparison of proportions.
Proteinuria is defined as >0.5 g/24 h or >40 mg/mmol creatinine in spot-urine.
mTOR, mammalian target of rapamycin; eGFR, estimated glomerular filtration rate.