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. 2019 Feb 5;9:3178. doi: 10.3389/fimmu.2018.03178

Table 2.

Baseline characteristics of responders and non-responders to Switzerland hemagglutinin antigen.

NoR
n = 20
R
n = 15
p-value*
CHARACTERISTICS AT TIME OF TRANSPLANTATION
Recipient
Age at transplantation (years) 53 ± 13 51 ± 16 0.74
Origin of renal disease, n (%) 0.80
  Glomerulonephritis 1 (5) 3 (20)
  Diabetes mellitus 3 (15) 2 (13)
  Vascular 6 (30) 4 (27)
  Genetic 4 (20) 3 (20)
  Uropathy 1 (5) 1 (7)
  Undetermined 5 (25) 2 (13)
Duration of dialysis (months) 21 ± 20 31 ± 43 0.83
DONOR
Donor age (years) 50 ± 14 48 ± 17 0.71
Donor sex, men, n (%) 14 (70) 11 (73) 1.0
Deceased donor, n (%) 17 (85) 14 (93) 0.69
Extended criteria donor, n (%) 6 (30) 7 (47) 0.48
TRANSPLANTATION
Number of HLA-A, B, C, DR, DQ mismatches 6.1 ± 1.5 5.2 ± 1.9 0.17
Combined kidney-pancreas transplantation, n (%) 2 (10) 1 (7) 1.00
Cold ischemia time (min) 677 ± 414 806 ± 490 0.40
Delayed graft function, n (%) 0 (0) 3 (21) 0.06
CHARACTERISTICS AT TIME OF VACCINATION
Time elapsed since transplantation (months) 23 ± 19 24 ± 15 0.77
IMMUNOSUPPRESSION
Induction therapy
   Thymoglobuline, n (%) 17 (85) 9 (60) 0.12
Maintenance regimen
  Tacrolimus, n (%) 19 (95) 10 (67) 0.06
  Ciclosporin, n (%) 1 (5) 5 (33)
  mTOR-Inhibitors, n (%) 2 (10) 1 (7) 1.00
  Mycophenolate, n (%) 18 (90) 14 (93) 1.00
  Azathioprin, n (%) 1 (5) 0
  Prednisone, n (%) 12 (60) 12 (80) 0.28
GRAFT FUNCTION
eGFR (ml/min/m2) 59 ± 22 61 ± 23 0.78
Proteinuria**, n (%) 3 (15) 3 (20) 1.00
*

Unpaired t-test was used for comparison of continuous variables and Fisher's exact test was used for comparison of proportions.

**

Proteinuria is defined as >0.5 g/24 h or >40 mg/mmol creatinine in spot-urine.

mTOR, mammalian target of rapamycin; eGFR, estimated glomerular filtration rate.