Table 3.

New antifungal drugs.

Antifungal drug	Mechanism of action
Aureobasidin A	Inhibition of inositol phosphoryl-ceramide (IPC) synthase (Aeed et al., 2009; Mor et al., 2015; Lazzarini et al., 2018)
APX001	Inhibition of glycosyl phosphatidylinositol (GPI) synthesis (Miyazaki et al., 2011; Wiederhold et al., 2015; Komath et al., 2018)
ASP2397	Disrupting the intracellular fungal biochemical machinery (Nakamura et al., 2017)
MGCD290	Inhibitor of HDAC (histone deacetylase) (Pfaller et al., 2009a, 2015)
FTY720	Modulator of sphingosine-1-phosphate receptor (Hagihara et al., 2013)
AR-12	Downregulation of host chaperones and inhibition of acetyl-CoA synthetase 1 (Koselny et al., 2016)
Nikkomycines	Inhibition of chitin synthase (Hector et al., 1990; Shubitz et al., 2014)